{"id":695,"date":"2026-06-03T09:34:14","date_gmt":"2026-06-03T09:34:14","guid":{"rendered":"https:\/\/idm-instituto.webs.upv.es\/wordpress\/?page_id=695"},"modified":"2026-09-01T10:34:22","modified_gmt":"2026-09-01T10:34:22","slug":"sym","status":"publish","type":"page","link":"https:\/\/idm-instituto.webs.upv.es\/wordpress\/index.php\/sym\/","title":{"rendered":"SYM"},"content":{"rendered":"\n
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Signal and Measurement<\/strong> – SYM<\/strong><\/p>\n<\/div>\n\n\n\n

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This multidisciplinary research group is a pioneer in the development of biosensors for applications in health, agri-food, and environmental fields. One of its main research lines focuses on holography in label-free biosensing, exploring holographic principles to design wearable biosensors and enhance assay sensitivity and selectivity through the development of diffractive hydrogels with optical transduction.<\/p>\n\n\n\n

The group also works on perovskite nanocrystals, including their synthesis, functionalization, characterization, and encapsulation for use as markers of proteins and nucleic acids in aqueous environments, taking advantage of their outstanding luminescent properties. Another key area is the production of protein-based bioreagents using recombinant techniques like phage display, enabling the generation of nanobodies, antibodies, miniproteins, and peptides with advanced properties like high affinity, selectivity, stability, and labeling capabilities essential for biosensing.<\/p>\n\n\n\n

In addition, the group develops analytical platforms by integrating its expertise into systems such as test strips and DNA and protein microarrays on polymeric surfaces (including chips, compact discs, hydrogels, membranes, and cellulose). These platforms incorporate microfluidics, optical systems, and dedicated hardware and software, providing comprehensive biosensing solutions.<\/p>\n\n\n\n

The group has a strong track record of innovation and collaboration, holding 15 patents (three international) and participating in eight European projects, acting as coordinator in one.<\/p>\n<\/div>\n<\/div>\n\n\n\n

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CV Prof. \u00c1ngel Maquieira Catal\u00e1<\/strong><\/p>\n\n\n\n

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\u00c1ngel Maquieira Catal\u00e1 holds a Ph.D. in Chemistry from the University of Valencia and is a Full and Emeritus Professor of Analytical Chemistry at the Polytechnic University of Valencia. He leads the \u201cSignal and Measurement in Chemistry (SYM)\u201d research group at the IDM.<\/p>\n\n\n\n

His research focuses on bioanalytics, developing biosensors and optoelectronic micro\/nanodevices to study biomarkers and analytes of clinical, food, and environmental interest, at basic and applied levels. He also works on perovskite nanomaterials, configuring PICs and biogratings to integrate electronic circuits and optical phenomena at the nanoscale to reduce nonspecific signals, alongside developing wearable materials and biosensors with holographic response.<\/p>\n\n\n\n

Regarding scientific outreach, Maquieira has published 298 articles (259 in Q1), with an h-index of 49. Over the past 5 years, he has supervised 12 doctoral theses. In 2013, he received the Royal Spanish Society of Chemistry (RSEQ) award for his research career in Analytical Chemistry.<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Research\u202fLines<\/strong>\u202f <\/p>\n\n\n\n

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Biosensors for health, agrotech and environment.<\/p>\n<\/div>\n\n\n\n

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Holography in label-free biosensing.<\/p>\n<\/div>\n\n\n\n

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Perovskite nanocrystals.<\/p>\n<\/div>\n\n\n\n

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Production of protein-based bioreagents.<\/p>\n<\/div>\n\n\n\n

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Highlighted<\/strong> Funding<\/strong><\/p>\n\n\n\n

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Tratamiento postcosecha. Estrategia anal\u00edtica para control de la aplicaci\u00f3n de fitosanitarios en planta y nivel de residuos en fruta (POSTFRUIT). AGROALNEXT\/2022\/054.<\/strong> Generalitat Valenciana (GVA). 2021-2025. \u00c1ngel Maquieira<\/em><\/p>\n\n\n\n

Ultra-sound combined with BIA and graphene FET-enhanced wearable sensing for decent health-monitoring (ULTRASENSE). 101130192<\/strong>. European Comission – Horizon RIA. 2024\u20132028. Mar\u00eda Jos\u00e9 Ba\u00f1uls Polo<\/em><\/p>\n\n\n\n

Malaria diagnosis and prognosis with an electrokinetic-driven aptamer-based lateral flow assay (MALDIPROT). 101150621<\/strong>. European Comission \u2013 Horizon TMA MSCA. 2024-2026. \u00c1ngel Maquieira<\/em><\/p>\n\n\n\n

Hydrogel-based advanced biosensors for in situ health monitoring. CIPROM\/2023\/18<\/strong>. Generalitat Valenciana (GVA). 2024\u20132028. Mar\u00eda Jos\u00e9 Ba\u00f1uls Polo<\/em><\/p>\n\n\n\n

Biosensores \u00f3pticos vestibles basados en hidrogeles. PID2022-140653OB-I00<\/strong>. Agencia Estatal de Investigaci\u00f3n (AEI). 2023\u20132026. Mar\u00eda Jos\u00e9 Ba\u00f1uls Polo<\/em><\/p>\n\n\n\n

Control y localizaci\u00f3n avanzada de riesgos en agua (CLARA). INNEST\/2025\/76<\/strong>. Instituto Valenciano de Competitividad Empresarial (IVACE+i). 2025\u20132027. Sergi Morais<\/em><\/p>\n\n\n\n

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Highlighted Publications<\/strong><\/p>\n\n\n\n

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Sena-Torralba, A.; Hernanz-Grimalt, A.; Martorell-Tejedor, S. et al. Reader Systems Used for Lateral Flow Assays. Lateral Flow Assays<\/em>. 2026<\/strong>. 91\u2013120. https:\/\/doi.org\/10.1016\/B978-0-443-23883-3.00005-2<\/a><\/p>\n\n\n\n

Patrone-Garcia, A.; Avella-Oliver, M.; Maquieira, \u00c1. Drying-Induced Salt Deposition Patterns as a Tool for Label-Free Protein Quantification. Biosensors<\/em>. 2025<\/strong>. 15, 520. https:\/\/doi.org\/10.3390\/bios15080520<\/a><\/p>\n\n\n\n

Cubells-G\u00f3mez, A.; Luc\u00edo, M. I.; Maquieira, \u00c1. et al. Polyrotaxane-Containing Hydrogels for Label-Free Detection of C-Reactive Protein (CRP) via Diffraction Gratings. Sensing and Bio-Sensing Research<\/em>. 2025<\/strong>. 49, 100849. https:\/\/doi.org\/10.1016\/j.sbsr.2025.100849<\/a><\/p>\n\n\n\n

Tortajada-Genaro, L. A. Massive Screening of Food Extracts for Quality Assessment and Standardization of Allergenic Activity. Biosensors<\/em>. 2024<\/strong>. 14, 615. https:\/\/doi.org\/10.3390\/bios14120615<\/a><\/p>\n\n\n\n

Lajoux, J.; Banguera-Ordo\u00f1ez, Y. D.; Sena-Torralba, A. et al. Breaking the Picomolar Barrier in Lateral Flow Assays Using Bright-Dtech\u2122 614\u2013Europium Nanoparticles for Enhanced Sensitivity. Microchemical Journal<\/em>. 2025<\/strong>. 209, 112864. https:\/\/doi.org\/10.1016\/j.microc.2025.112864<\/a><\/p>\n\n\n\n

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Prof. Sergi \u202fMorais Ezquerro<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Prof. Luis\u202fTortajada<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Prof. M\u00aa Jos\u00e9\u202fBa\u00f1uls Polo<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Prof. Pilar Arag\u00f3n Revuelta<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Prof. Miquel\u202fAvell\u00e1 <\/p>\n<\/div>\n<\/div>\n\n\n\n

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Prof. Miguel \u202f\u00c1ngel\u202f Gonz\u00e1lez Mart\u00ednez<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Prof. M\u00aa Victoria Gonz\u00e1lez Pedro<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Prof. Mar\u00eda Isabel\u202fLuc\u00edo Benito<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Prof. Sara Martorell<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Dr. Aitor Cubells G\u00f3mez<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Dr. Yulieth Deifan Banguera Ord\u00f3\u00f1ez<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Manuel Ros Sirvent<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Josu\u00e9 Lombeyda Manzo<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Pamela Abigail Chillagana Pilapanta<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Kristian Nickolaev Parapanov<\/p>\n<\/div>\n<\/div>\n\n\n\n

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<\/p>\n","protected":false},"excerpt":{"rendered":"

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