María Del Mar Sánchez Martín, Victoria Moreno-Manzano, Esther Giraldo

Optogenetic innovations in stem cell therapy: Illuminating the path for transplanted cells after spinal cord injury

Neural Regeneration Research · DOI: 10.4103/NRR.NRR-D-25-01817

María del Mar Sánchez‑Martín, Esther Giraldo, Ana Alastrue‑Agudo, Eric López‑Mocholi, Samuel Martín‑Pérez, Loris Maninno, Guillem Paniagua Soriano, Ana Isabel Fraga Sánchez, Javier Monreal‑Trigo, José Manuel Terrés‑Haro, Quique Vidal Beneyto, Ana Conesa, Erna van Niekerk, Mark Tuszynski, Victoria Moreno‑Manzano

Fetal rat neural progenitor cell transplantation after spinal cord injury improves motor recovery following optogenetic stimulation

Molecular Therapy · DOI: 10.1016/j.ymthe.2025.07.041

Beatriz Martínez-Rojas, Samuel Martín-Pérez, Esther Giraldo, Eric Lopez-Mocholi, Ana Alastrue, Yuniesky Andrade-Talavera, Jose Prius-Mengual, Guillem Paniagua, Maria Pedraza, Sonia Hingorani, Benjamin R. Rost, Dietmar Schmitz, Marta Llansola, Vicente Felipo, Antonio Rodríguez-Moreno & Victoria Moreno-Manzano

Stimulation of corticospinal neurons by optogenetic cAMP inductions promotes motor recovery after spinal cord injury in female rats via raphespinal tract modulation

Nature Communications · DOI: 10.1038/s41467-025-61018-3

Irene Lladosa Martinez, Susana Torres-Martínez, Ester Munera-Maravilla, Sarai Tomás-Pérez, Josep Marí-Alexandre, Sandra Gallach, Juan Gilabert-Estellés, Eloisa Jantus, Silvia Calabuig-Fariñas, Cristina Caballero

Clinical Utility of Soluble Immune Mediators and cfDNA in Endometrial Cancer

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2025.100384

Ester Munera-Maravilla, Susana Torres-Martínez, Paula Espinosa-Olarte, Inma Hernández, Marais Mosqueda, Nera Fernández, Sandra Gallach, Cristina Caballero, Silvia Calabuig-Fariñas, Eloisa Jantus-Lewintre

Circulating immune signatures as predictors of immunotherapy response in non-small cell lung cancer

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2025.100362

E. Munera, S. Torres-Martinez, A. Moreno-Manuel, P. Espinosa-Olarte, S. Gallach, M. Mosqueda, A. Blasco, C. Caballero, S. Calabuig-Fariñas, E. Jantus-Lewintre

EP.06.77 Exploring the Impact of Peripheral Immune Landscape on Immunotherapy Outcomes in Non-Small Cell Lung Cancer

Journal of Thoracic Oncology · DOI: 10.1016/j.jtho.2025.09.1371

Eloisa Jantus, Ana Patiño-García, Angel Diaz-Lagares

Reading Between the Lines: Circulating Tumor DNA Dynamics Illuminate Immunotherapy Outcomes in Lung Squamous Cell Carcinoma

Journal of Thoracic Oncology · DOI: 10.1016/j.jtho.2025.07.011

Juan Carlos Álvarez-Pérez, Juan Sanjuán-Hidalgo, Alberto M. Arenas, Ivan Hernández-Navas, Maria S. Benitez‑Cantos, Alvaro Andrades, Silvia Calabuig-Fariñas, Eloisa Jantus-Lewintre, Luis Paz-Ares, Irene Ferrer, Pedro P. Medina

High-fidelity Cas9-mediated targeting of KRAS driver mutations restrains lung cancer in preclinical models

Nature Communications · DOI: 10.1038/s41467‑025‑62350‑4

Jenifer García‑Fernández, Sandra Díez‑Villares, María Cascallar, Laura Rivadulla Costa, Ana S. Martins, Soraya Groba de Antas, Maria Cristina Tarasco, Elvira Pantano, Giulia Taiè, Giulia Bertolini, Marta García‑Hernández, Miguel Moreno, M. Elena Martín, Ester Munera‑Maravilla, Silvia Calabuig‑Fariñas, Laura Taina‑González, Miguel G. Blanco, Rafael López‑López, Alar Ainla, Sara Abalde‑Cela, Catarina Gonçalves, Miguel Xavier, Lorena Diéguez, Eloisa Jantus‑Lewintre, Luca Roz, Víctor M. González, María de la Fuente Freire

Targeted delivery of therapeutics to metastatic lung cancer cells using aptamer-conjugated nanoemulsions

Journal of Controlled Release · DOI: 10.1016/j.jconrel.2025.114031

Clara Mayo de las Casas, Eloisa Jantus‑Lewintre, Sebastián Ortiz Reina, Ana Drozdowskyj, Pablo Cerezuela‑Fuentes, José Luis Manzano, Pablo Ayala de Miguel, Ana Arance Fernandez, Miguel Angel Berciano‑Guerrero, Almudena Garcia‑Castaño, Teresa Puertolas, Guillermo Crespo, Maria Quindos‑Varela, Juan Francisco Rodriguez‑Moreno, Alfonso Berrocal, Eva Muñoz‑Couselo, Enrique Espinosa, Joselyn Valarezo, Susana Muñoz, Silvia Calabuig‑Fariñas, Miguel Angel Molina, Rafael Rosell, Joan Anton Puig‑Butille, Maria Gonzalez‑Cao

Cross-method comparison for BRAF p.V600 mutation cfDNA testing in Melanoma: BRAFI study

EJC Skin Cancer · DOI: 10.1016/j.ejcskn.2025.100738

Nicola Fusco, Konstantinos Venetis, Francesco Pepe, Omshree Shetty, Silvia Calabuig Farinas, Simon Heeke, Julia V. Burnier, Simon J. Patton, Ellen Heitzer, Giovanni Nigita, Paul Hofman, Maria Jose Serrano, Massimo Cristofanilli, Eloisa Jantus‑Lewintre, David R. Gandara, Christian Rolfo, Umberto Malapelle

International Society of Liquid Biopsy (ISLB) perspective on minimal requirements for ctDNA testing in solid tumors

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2025.100301

Paula Espinosa‑Olarte, E. Munera Maravilla, P.J. Gómez García, A. Blasco Cordellat, S. Martínez, S. Calabuig Fariñas, L. Navarro‑Cerveró, A. Navarro, A.F. Díaz, E. Jantus‑Lewintre, C. Caballero Díaz

367P: Clinical characteristics and ctDNA as prognostic tools in KRAS-mutated NSCLC during first line treatment (1L)

Journal of Thoracic Oncology · DOI: 10.1016/S1556-0864(25)00559-3

Eloisa Jantus‑Lewintre, Alessandra Rappa, Dina Ruano, Demi van Egmond, Sandra Gallach, Dilce Gozuyasli, Cecília Durães, José Luis Costa, Carlos Camps, Ludovic Lacroix, Karl Kashofer, Tom van Wezel, Massimo Barberis

Multicenter In-House Evaluation of an Amplicon-Based Next−Generation Sequencing Panel for Comprehensive Molecular Profiling

Molecular Diagnosis & Therapy · DOI: 10.1007/s40291-024-00766-2

Francisco Exposito, Miriam Redrado, Diego Serrano, Silvia Calabuig‑Fariñas, Aida Bao‑Caamano, Sandra Gallach, Eloisa Jantus‑Lewintre, Ángel Díaz‑Lagares, Aitor Rodriguez‑Casanova, Juan Sandoval, Edurne San Jose‑Eneriz, Javier Garcia, Esther Redin, Yaiza Senent, Sergio Leon, Ruben Pio, Rafael Lopez, Julen Oyarzabal, Antonio Pineda‑Lucena, Xabier Agirre, Luis M. Montuenga, Felipe Prosper, Alfonso Calvo

G9a/DNMT1 co-targeting inhibits non-small cell lung cancer growth and reprograms tumor cells to respond to cancer-drugs through SCARA5 and AOX1

Cell Death and Disease · DOI: 10.1038/s41419‑024‑07156‑w

Andrea Moreno-Manuel, Susana Torres-Martíne, Sandra Gallach, Marais Mosqueda, Maria Luz Bellón, Eva Escorihuela, Ana Blasco, Silvia Calabuig-Fariñas, Carlos Camps, Eloisa Jantus-Lewintre

Non-invasive immunogram to characterize and monitor immune status in non-small cell lung cancer patients treated with immunotherapy.

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2024.100240

Silvia Calabuig-Fariñas, Susana Torres-Martínez, Javier Iranzo, Lara Navarro-Cerveró, Ester Munera-Maravilla, Marais Mosqueda-Frometa, Sandra Gallach, Cristina Caballero, Ana Blasco, Eloisa Janus-Lewintre

A first-line approach: Liquid biopsy-guided osimertinib therapy for EGFR-mutated NSCLC

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2024.100195

Susana Torres-Martínez, Elena Duréndez-Saéz, Sandra Gallach-García, Eva Escorihuela, Ester Munera-Maravilla, Paula Espinosa, Ana Blasco, Cristina Caballero , Silvia Calabuig-Fariñas, Eloisa Jantus-Lewintre

NSCLC exosomes: Unlocking biomarker potential

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2024.100188

Susana Torres-Martínez, Elena Duréndez-Saéz, Marais Mosqueda, Ester Munera-Maravilla, Mari Luz Bellón, Paula Espinosa, Ana Blasco, Cristina Caballero, Silvia Calabuig-Fariñas, Eloisa Jantus-Lewintre

Assessing mutational status in NSCLC through exosomal liquid biopsies

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2024.100245

Eloisa Jantus Lewintre, Silvia Calabuig Fariñas, Joan Anton Puig-Butille, Sebastián Ortiz Reina, Ana Drozdowskyj, Pablo Cerezuela Fuentes, José Luis Manzano Mozo, Pablo Ayala de Miguel, María Gonzalez Cao, Clara Mayo de las Casas

BRAF V600 mutations detection in melanoma: A cross-methodological study using CFDNA

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2024.100207

Ester Munera-Maravilla, Susana Torres-Martínez, Marais Mosqueda, Maria Luz Bellón, Lara Navarro, Paula Espinosa-Olarte, Ana Blasco-Cordellat, Cristina Caballero, Eloisa Jantus-Lewintre, Silvia Calabuig-Fariñas

Liquid biopsy for monitoring response in KRAS-mutated NSCLC patients treated with first-line immunotherapy

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2024.100186

Carolina Reduzzi, Eleonora Nicolo, Surbhi Singhal, Konstantinos Venetis, Ana Ortega-Franco, Diego de Miguel-Perez, Angelo Dipasquale, Mohamed A. Gouda, Erick F. Saldanha, Pashtoon M. Kasi, Eloisa Jantus-Lewintre, Nicola Fusco, Umberto Malapelle, David R. Gandara, Christian Rolfo, Maria Jose Serrano, Massimo Cristofanilli

Unveiling the impact of circulating tumor cells: Two decades of discovery and clinical advancements in solid tumors

Critical Reviews in Oncology/Hematology · DOI: 10.1016/j.critrevonc.2024.104483

Rafael Rosell, Eloisa Jantus‑Lewintre, Peng Cao, Xueting Cai, Baojuan Xing, Masaoki Ito, José Luis Gomez‑Vazquez, Mireia Marco‑Jordán, Silvia Calabuig‑Fariñas, Andrés Felipe Cardona, Jordi Codony‑Servat, Jessica Gonzalez, Kevin València‑Clua, Andrés Aguilar, Carlos Pedraz‑Valdunciel, Zahra Dantes, Anisha Jain, S Chandan, Miguel Ángel Molina‑Vila, Oscar Arrieta, Macarena Ferrero, Carlos Camps y María González‑Cao

KRAS-mutant non-small cell lung cancer (NSCLC) therapy based on tepotinib and omeprazole combination

Cell Communication and Signaling · DOI: 10.1186/s12964‑024‑01667‑x

Maria González‑Cao, Xueting Cai, Jilian Wilhelmina Paulina Bracht, Xuan Han, Yang Yang, Carlos Pedraz‑Valdunciel, Teresa Morán, Javier García‑Corbacho, Andrés Aguilar, Reyes Bernabé, Pedro De Marchi, Luciane Sussuchi da Silva, Leticia Ferro Leal, Rui Manuel Reis, Jordi Codony‑Servat, Eloísa Jantus‑Lewintre, Miguel Angel Molina‑Vila, Peng Cao, Rafael Rosell

HMGB1 Expression Levels Correlate with Response to Immunotherapy in Non-Small Cell Lung Cancer

Lung Cancer: Targets and Therapy · DOI: 10.2147/LCTT.S455034

Ana Patiño‑García, Elizabeth Guruceaga, María Pilar Andueza, Marimar Ocón, Jafait Junior Fodop Sokoudjou, Nicolás de Villalonga Zornoza, Gorka Alkorta‑Aranburu, Ibon Tamayo Uria, Alfonso Gurpide, Carlos Camps, Eloisa Jantus‑Lewintre, María Navamuel‑Andueza, Miguel F. Sanmamed, Ignacio Melero, Mohamed Elgendy, Juan Pablo Fusco, Javier Zulueta, Juan Pablo de Torres, Gorka Bastarrika, Luis Seijo, Ruben Pio, Luis M. Montuenga, Mikel Hernáez, Idoia Ochoa, José Luis Perez‑Gracia

Whole exome sequencing and machine learning germline analysis of individuals presenting with extreme phenotypes of high and low risk of developing tobacco-associated lung adenocarcinoma

EBioMedicine · DOI: 10.1016/j.ebiom.2024.105048

Rafael Sirera; Manuel Beltrán-Visiedo; Lorenzo Galluzzi

A novel pharmacological entity toward integrated multimodal immunotherapy

Trends in Pharmacological Sciences · DOI: 10.1016/j.tips.2024.12.001

Rafael Sirera; Manuel Beltrán-Visiedo; Lorenzo Galluzzi

Targeting immune evasion in hepatocellular carcinoma-initiating cells

Trends in Immunology · DOI: 10.1016/j.it.2024.12.002

Dong Wei; Daqiang Sun; Rafael Sirera; Muhammad Zubair Afzal; Tracy L. Leong; Xin Li; Yuhang Wang

Overexpression of MRPL19 in predicting poor prognosis and promoting the development of lung adenocarcinoma

Translational Lung Cancer Research · DOI: 10.21037/tlcr-23-306

Susana Torres‑Martínez, Silvia Calabuig‑Fariñas, Sandra Gallach, Marais Mosqueda, Ester Munera‑Maravilla, Rafael Sirera, Lara Navarro, Ana Blasco, Carlos Camps, Eloisa Jantus‑Lewintre

Circulating Immune Proteins: Improving the Diagnosis and Clinical Outcome in Advanced Non-Small Cell Lung Cancer

International Journal of Molecular Sciences (IJMS) · DOI: 10.3390/ijms242417587

Alejandro Moreno‑Manuel, Susana Torres‑Martínez, Ana Boada, María Bellón, Esther Escorihuela, Silvia Calabuig‑Fariñas, Rafael Sirera, Carlos Camps, Ana Blasco, Eloísa Jantus‑Lewintre

Analysis of Immunoregulatory Genes Expression in PBMCs as Potential Predictive and Prognostic Biomarkers in NSCLC Patients Treated with Immunotherapy

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2023.100087

S. Gallach Garcia, M. Mosqueda, A. Moreno‑Manuel, L. Navarro, S. Torres‑Martínez, E. Munera‑Maravilla, A. Blasco, S. Calabuig‑Fariñas, C. Camps, E. Jantus‑Lewintre

Next Generation Sequencing in Liquid Biopsies: Towards Personalized Cancer Treatment.

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2023.100026

A. Moreno Manuel, N. Dong, S. Gallach, S. Torres‑Martínez, M. Mosqueda, S. Calabuig‑Fariñas, R. Sirera, A. Blasco, C. Camps, E. Jantus‑Lewintre

TCR-β Repertoire as a Source of Biomarkers for anti-PD1 Treatment Alone or in Combination With Chemotherapy in Advanced-stage NSCLC Patients

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2023.100088

S. Torres‑Martínez, A. Fernández, J. Carbonell, E. Escorihuela, N. Juciute, I. Ramos, A. Berrocal, E. Jantus‑Lewintre, C. Camps, S. Calabuig‑Fariñas

Prognostic and Predictive Non-Invasive Biomarkers in Cutaneous Melanoma Treated With Anti PD-1 Antibodies

The Journal of Liquid Biopsy · DOI: 10.1016/j.jlb.2023.100058

E. Munera‑Maravilla, C. Ortuño Moya, S. Gallach, C. Labrandero, A. Moreno‑Manuel, M. Bellón‑Robles, S. Calabuig‑Fariñas, A. Esteve‑Martínez, E. Jantus‑Lewintre

Clinical Utility of Liquid Biopsy in the Diagnosis and Monitoring of Patients Affected by PROS Syndromes

· DOI: 10.1016/j.jlb.2023.100045

R. Rosell, A. Jain, J. Codony‑Servat, C. Shivamallu, S. Prasad Kollur, A. Prasad, E. Jantus‑Lewintre, M. Ito, A.F. Cardona, O. Arrieta, P. Cao, X. Cai, B. Xing, C. Pedraz‑Valdunciel, Z. Dantes, I. Sullivan, A. Aguilar, M.A. Molina‑Vila, M. González‑Cao

MA04.09 The MET Inhibitor Tepotinib Potentially Inhibits KRAS G12C and SHOC2 in KRAS G12C Non-Small Cell Lung Cancer (NSCLC)

Journal of Thoracic Oncology · DOI: 10.1016/j.jtho.2023.09.141

Irati Macaya, Marta Roman, Connor Welch, Rodrigo Entrialgo‑Cadierno, Marina Salmon, Alba Santos, Iker Feliu, Joanna Kovalski, Ines Lopez, Maria Rodriguez‑Remirez, Sara Palomino‑Echeverria, Shane M. Lonfgren, Macarena Ferrero, Silvia Calabuig, Iziar A. Ludwig, David Lara‑Astiaso, Eloisa Jantus‑Lewintre, Elizabeth Guruceaga, Shruthi Narayanan, Mariano Ponz‑Sarvise, Antonio Pineda‑Lucena, Fernando Lecanda, Davide Ruggero, Purvesh Khatri, Enrique Santamaria, Joaquin Fernandez‑Irigoyen, Irene Ferrer, Luis Paz‑Ares, Matthias Drosten, Mariano Barbacid, Ignacio Gil‑Bazo, Silve Vicent

Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer

Nature Communications · DOI: 10.1038/s41467-023-41828-z

C. Lazaro, E. Jantus Lewintre, S. Zazo, S. Pérez, N. Carvajal Garcia, D. Azuara, M. González Acosta, M. Varela, S. Torres‑Martínez, S. Gallach Garcia, M. Colomar, M. Sanchez Ares, R. Perez‑Becerra, J.R. Antunez, M. Orellana, M. Lencina, I. Abdulkader Nallib, C.J.C. Camps Herrero, X. Matias‑Guiu, F. Rojo

773P Real-world results of homologous recombination deficiency testing: Comparison between two methods on 2,655 ovarian cancer patients in Spain

Annals of Oncology · DOI: 10.1016/j.annonc.2023.09.1951

N. Juciute, L.A. Boada‑Acosta, S. Torres‑Martínez, E. Escorihuela, E. Munera Maravilla, M. Mosqueda‑Frometa, M. Castellote‑Borrell, A. Rodriguez, N. Miranda, L. Roz, L. Navarro‑Cerveró, B. Blanco, J. Guasch, R. Guijarro, E. Pastor‑Martinez, S. Calabuig Fariñas, C. Camps Herrero, E. Jantus Lewintre

2250P Exploring tumor microenvironment in lung cancer through patient-derived 3D models

Annals of Oncology · DOI: 10.1016/j.annonc.2023.09.1278

E. Jantus Lewintre, A. Rappa, D. Ruano, S. Gallach Garcia, C.J.C. Camps Herrero, L. Lacroix, K. Kashofer, T. van Wezel, M. Barberis

219P Multicentric evaluation of amplicon-based next-generation sequencing solution for local comprehensive molecular tumor profiling

Annals of Oncology · DOI: 10.1016/j.annonc.2023.09.2942

R. Rosell, A. Jain, J. Codony‑Servat, C. Shivamallu, S.P. Kollur, A. Prasad, P. Vishwanath, E. Jantus Lewintre, M. Ito, A.F. Cardona Zorrilla, O.G. Arrieta Rodriguez, C. Pedraz‑Valdunciel, J. González Nieto, A. Aguilar, M.A. Molina‑Vila, M. Gonzalez Cao

2325P Selinexor (XPO1 inhibitor) in combination with tepotinib (MET inhibitor) potentially inhibits SHOC2 and KRAS G12C in KRAS G12C mutant non-small cell lung cancer

Annals of Oncology · DOI: 10.1016/j.annonc.2023.09.1354

Susana Torres-Martínez, Silvia Calabuig-Fariñas, Andrea Moreno-Manuel, Giulia Bertolini, Alejandro Herreros-Pomares, Eva Escorihuela, Elena Duréndez-Saéz, Ricardo Guijarro, Ana Blasco, Luca Roz, Carlos Camps, Eloisa Jantus-Lewintre

Soluble galectin‐3 as a microenvironment‐relevant immunoregulator with prognostic and predictive value in lung adenocarcinoma

Molecular Oncology · DOI: 10.1002/1878-0261.13505

Andrés Arboleda‑García, Ivan Alarcon‑Ruiz, Lissette Boada‑Acosta, Yadira Boada, Alejandro Vignoni, Eloisa Jantus‑Lewintre

Advancements in synthetic biology-based bacterial cancer therapy: A modular design approach

Critical Reviews in Oncology/Hematology · DOI: 10.1016/j.critrevonc.2023.104088

Rafael Rosell, Anisha Jain, Jordi Codony-Servat, Eloisa Jantus-Lewintre, Blake Morrison, Jordi Barretina Ginesta and María González-Cao

Biological insights in non-small cell lung cancer

Cancer Biology & Medicine · DOI: 10.20892/j.issn.2095-3941.2023.0108

Jose Luis Perez-Gracia, Elisabet Guruceaga, Maria Pilar Andueza, Marimar Ocon, Nicolas de VIllalonga Zornoza, Jafait Junior Fodop Sokoudjou, Gorka Alkorta-Aranburu, Carlos Camps, Eloisa Jantus-Lewintre, Maria Navamuel Andueza, Miguel F. Sanmamed, Alfonso Gurpide, Ignacio Melero Bermejo, Mohamed Elgendy, Juan Alberto Perez Valencia, Mikel Hernaez, Ruben Pio Oses, Luis M. Montuenga, Idoia Ochoa, Ana Patiño-García

Whole exome sequencing and machine learning germline analysis of individuals presenting with phenotypes of extreme high and low risk of developing tobacco-induced lung adenocarcinoma.

Journal of Clinical Oncology · DOI: 10.1200/JCO.2023.41.16_suppl.10507

M. Nunez Abad, S. Torres‑Martínez, M. Mosqueda‑Frometa, M.T. Taberner‑Bonastre, J.Á. García García, F. Ben Hammou El Majdoubi, E. Jantus Lewintre, C. Camps Herrero, V. Iranzo, S. Calabuig Fariñas

17P Prognostic and predictive non-invasive biomarkers in early triple-negative breast cancer (TNBC) treated with neoadjuvant chemotherapy (NACT)

ESMO Open · DOI: 10.1016/j.esmoop.2023.101241

M. Gonzalez‑Cao, X. Cai, J.W.P. Bracht, X. Han, Y. Yang, C. Pedraz, M.T. Moran Bueno, J. García‑Corbacho, A. Aguilar, R. Bernabe Caro, P.R. De Marchi, L. Sussuchi Da Silva, L. Ferro Leal, R.M. Reis, J. Codony‑Servat, E. Jantus Lewintre, M.A. Molina‑Vila, P. Cao, R. Rosell

178P Targeting XPO1-dependent nuclear export of HMGB1 in non-small cell lung cancer

Journal of Thoracic Oncology · DOI: 10.1016/S1556-0864(23)00432-X

R. Rosell, J.L. Gómez‑Vázquez, E. Jantus Lewintre, M. Ito, P. Cao, X. Cai, B. Xing, S. Calabuig Fariñas, A.F. Cardona, J.K. Rodríguez, M. Marco Jordán, C. Pedraz Valdunciel, M.A. Molina‑Vila, J. Codony‑Servat, Z. Dantes, A. Aguilar, I.G. Sullivan, I. Moya Horno, L. Cirera, M. Gonzalez‑Cao

199P Suppression of mutant Kirsten-RAS (KRAS G12C) non-small cell lung cancer (NSCLC) resistance to KRAS G12C inhibitors by dual inhibition of hepatocyte growth factor receptor (MET) and V-ATPase

Journal of Thoracic Oncology · DOI: 10.1016/S1556-0864(23)00452-5

Alejandro Herreros‑Pomares, David Hervás, Leticia Bagan‑Debón, Eloísa Jantus‑Lewintre, Concepción Gimeno‑Cardona, José Bagan

On the Oral Microbiome of Oral Potentially Malignant and Malignant Disorders: Dysbiosis, Loss of Diversity, and Pathogens Enrichment

International Journal of Molecular Sciences (IJMS) · DOI: 10.3390/ijms24043466

María del Mar Sánchez‑Martín, Esther Giraldo, Fernando Gisbert Roca, Ana Alastrue‑Agudo, Cristina Martínez‑Ramos, Manuel Monleón Pradas, Victoria Moreno‑Manzano

Acute transplantation of NPC on electrospun poly-lactic acid membranes containing curcumin into the injured spinal cord reduces neuronal degeneration

Frontiers in Biomaterials Science · DOI: 10.3389/fbiom.2023.1298894

Esther Giraldo, Pablo Bonilla, Mara Mellado, Pablo Garcia‑Manau, Carlota Rodo, Ana Alastrue, Eric Lopez, Elena Carreras Moratonas, Ferran Pellise, Snežana Đorđević, María J. Vicent, Victoria Moreno Manzano

Transplantation of Human-Fetal-Spinal-Cord-Derived NPCs Primed with a Polyglutamate-Conjugated Rho/Rock Inhibitor in Acute Spinal Cord Injury

Cells · DOI: 10.3390/cells11203304

Beatriz Martínez-Rojas, Esther Giraldo, Rubén Grillo-Risco, Marta R. Hidalgo, Eric López-Mocholi, Ana Alastrue-Agudo, Francisco García-García, Victoria Moreno-Manzano

NPC transplantation rescues sci-driven cAMP/EPAC2 alterations, leading to neuroprotection and microglial modulation

Cellular and Molecular Life Sciences · DOI: 10.1007/s00018-022-04494-w

Marina Meri‑Abad, Andrea Moreno‑Manuel, Sandra Gallach García, Silvia Calabuig‑Fariñas, Rafael Sirera Pérez, Carlos Camps Herrero, Eloisa Jantus‑Lewintre

Clinical and technical insights of tumour mutational burden in non-small cell lung cancer

Critical Reviews in Oncology/Hematology · DOI: 10.1016/j.critrevonc.2022.103891

Alejandro Herreros‑Pomares, Paula Doria, Sandra Gallach, Marina Meri‑Abad, Ricardo Guijarro, Silvia Calabuig‑Fariñas, Carlos Camps, Eloísa Jantus‑Lewintre

A Sonic Hedgehog Pathway Score to Predict the Outcome of Resected Non-Small Cell Lung Cancer Patients

Annals of Surgical Oncology · DOI: 10.1245/s10434-022-12565-2

Elena Duréndez‑Sáez, Silvia Calabuig‑Fariñas, Susana Torres‑Martínez, Andrea Moreno‑Manuel, Alejandro Herreros‑Pomares, Eva Escorihuela, Marais Mosqueda, Sandra Gallach, Ricardo Guijarro, Eloisa Jantus‑Lewintre

Analysis of Exosomal Cargo Provides Accurate Clinical, Histologic and Mutational Information in Non-Small Cell Lung Cancer

Cancers · DOI: 10.3390/cancers14133216

Pilar Baldominos; Olga Barreiro; Ulrich von Andrian; Rafael Sirera; Paula Montero-Llopis; Judith Agudo

Protocol to isolate live single cells while retaining spatial information by combining cell photolabeling and FACS

STAR Protocols · DOI: 10.1016/j.xpro.2022.101795

Christian Rolfo, Noy Meshulami, Alessandro Russo, Florian Krammer, Adolfo García-Sastre, Philip C. Mack, Jorge E. Gomez, Nina Bhardwaj, Amin Benyounes, Rafael Sirera, Amy Moore, Nicholas Rohs, Claudia I. Henschke, David Yankelevitz, Jennifer King, Yu Shyr, Paul A. Bunn Jr., John D. Minna, Fred R. Hirsch

Lung Cancer and SARS-CoV-2 infection: Identifying important knowledge gaps for investigation

Journal of Thoracic Oncology · DOI: 10.1016/j.jtho.2021.11.001

Umberto Malapelle, Pasquale Pisapia, Alfredo Addeo, Oscar Arrieta, Beatriz Bellosillo, Andres F. Cardona, Massimo Cristofanilli, Diego De Miguel‑Perez, Valeria Denninghoff, Ignacio Durán, Eloísa Jantus‑Lewintre, Pier Vitale Nuzzo, Ken O’Byrne, Patrick Pauwels, Edward M. Pickering, Luis E. Raez, Alessandro Russo, Maria José Serrano, David R. Gandara, Giancarlo Troncone, Christian Rolfo

Liquid Biopsy from research to clinical practice: focus on Non-Small Cell Lung Cancer

Expert Review of Molecular Diagnostics · DOI: 10.1080/14737159.2021.1985468

Eloisa Jantus‑Lewintre, Bartomeu Massutí Sureda, José Luis González Larriba, Delvys Rodríguez‑Abreu, Oscar Juan, Ana Blasco, Manuel Dómine, Mariano Provencio Pulla, Javier Garde, Rosa Álvarez, Inmaculada Maestu, Ramón Pérez de Carrión, Ángel Artal, Christian Rolfo, Javier de Castro, Mónica Guillot, Juana Oramas, Ramón de las Peñas, Lioba Ferrera, Natividad Martínez, Òlbia Serra, Rafael Rosell, Carlos Camps

Prospective Exploratory Analysis of Angiogenic Biomarkers in Peripheral Blood in Advanced NSCLC Patients Treated With Bevacizumab Plus Chemotherapy: The ANGIOMET Study

Frontiers in Oncology · DOI: 10.3389/fonc.2021.695038

Alejandro Herreros‑Pomares, Carlos Llorens, Beatriz Soriano, Feiyu Zhang, Sandra Gallach, Leticia Bagan, Judith Murillo, Eloísa Jantus‑Lewintre, José Bagan

Oral microbiome in Proliferative Verrucous Leukoplakia exhibits loss of diversity and enrichment of pathogens

Oral Oncology · DOI: 10.1016/j.oraloncology.2021.105404

Estela Sánchez-Herrero, Roberto Serna-Blasco, Vadym Ivanchuk, Rosario García-Campelo, Manuel Dómine Gómez, José M. Sánchez, Bartomeu Massutí, Noemi Reguart, Carlos Camps, Sandra Sanz-Moreno, Silvia Calabuig-Fariñas, Eloísa Jantus-Lewintre, Magdalena Arnal, Dietmar Fernández-Orth, Virginia Calvo, Víctor González-Rumayor, Mariano Provencio, Atocha Romero

NGS‐based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment

Molecular Oncology · DOI: 10.1002/1878-0261.13033

Cora Palanca‑Ballester, Aitor Rodriguez‑Casanova, Susana Torres, Silvia Calabuig‑Fariñas, Francisco Exposito, Diego Serrano, Esther Redin, Karmele Valencia, Eloisa Jantus‑Lewintre, Angel Diaz‑Lagares, Luis Montuenga, Juan Sandoval, Alfonso Calvo

Cancer Epigenetic Biomarkers in Liquid Biopsy for High Incidence Malignancies

Cancers · DOI: 10.3390/cancers13123016

Ning Dong, Andrea Moreno‑Manuel, Silvia Calabuig‑Fariñas, Sandra Gallach, Feiyu Zhang, Ana Blasco, Francisco Aparisi, Marina Meri‑Abad, Ricardo Guijarro, Rafael Sirera, Carlos Camps, Eloísa Jantus‑Lewintre

Characterization of Circulating T Cell Receptor Repertoire Provides Information about Clinical Outcome after PD-1 Blockade in Advanced Non-Small Cell Lung Cancer Patients

Cancers · DOI: 10.3390/cancers13122950

Ning Dong, Andrea Moreno‑Manuel, Silvia Calabuig‑Fariñas, Sandra Gallach, Feiyu Zhang, Ana Blasco, Francisco Aparisi, Marina Meri‑Abad, Ricardo Guijarro, Rafael Sirera, Carlos Camps, Eloísa Jantus‑Lewintre

Analysis of the Gut Microbiota: An Emerging Source of Biomarkers for Immune Checkpoint Blockade Therapy in Non-Small Cell Lung Cancer

Cancers · DOI: 10.3390/cancers13112514

Mariano Provencio, Roberto Serna‑Blasco, Fabio Franco, Virgina Calvo, Ana Royuela, Milda Auglytė, Alfredo Sánchez‑Hernández, María de Julián Campayo, Carlos García‑Girón, Manuel Dómine, Ana Blasco, José M. Sánchez, Juana Oramas, Joaquim Bosch‑Barrera, María Á. Sala, María Sereno, Ana L. Ortega, Luis Chara, Berta Hernández, Airam Padilla, Juan Coves, Remedios Blanco, José Balsalobre, Xabier Mielgo, Coralia Bueno, Eloisa Jantus‑Lewintre, Miguel Á. Molina‑Vila, Atocha Romero

Analysis of circulating tumour DNA to identify patients with epidermal growth factor receptor–positive non-small cell lung cancer who might benefit from sequential tyrosine kinase inhibitor treatment

European Journal of Cancer · DOI: 10.1016/j.ejca.2021.02.031

Valentina Dikova, Eloisa Jantus, Jose V Bagan

Potential Non-Invasive Biomarkers for Early Diagnosis of Oral Squamous Cell Carcinoma

Journal of Clinical Medicine (JCM) · DOI: 10.3390/jcm10081658

Alejandro Herreros‑Pomares, Carlos Llorens, Beatriz Soriano, Leticia Bagan, Andrea Moreno, Silvia Calabuig‑Fariñas, Eloísa Jantus‑Lewintre, José Bagan

Differentially methylated genes in proliferative verrucous leukoplakia reveal potential malignant biomarkers for oral squamous cell carcinoma

Oral Oncology · DOI: 10.1016/j.oraloncology.2021.105191

Stephen P. Finn, Alfredo Addeo, Urania Dafni, Erik Thunnissen, Lukas Bubendorf, Line Bille Madsen, Wojciech Biernat, Eric Verbeken, Javier Hernandez‑Losa, Antonio Marchetti, Richard Cheney, Arne Warth, Ernst‑Jan M. Speel, Anne Marie Quinn, Kim Monkhorst, Eloisa Jantus‑Lewintre, Verena Tischler, Nesa Marti, Georgia Dimopoulou, Miguel A. Molina‑Vila, Roswitha Kammler, Keith M. Kerr, Solange Peters, Rolf A. Stahel

Prognostic impact of KRAS G12C mutation in patients with NSCLC: results from the ETOP Lungscape Project

Journal of Thoracic Oncology · DOI: 10.1016/j.jtho.2021.02.016

Alejandro Herreros‑Pomares, Xuan Zhou, Silvia Calabuig‑Fariñas, Se‑Jun Lee, Susana Torres, Timothy Esworthy, Sung Yun Hann, Eloísa Jantus‑Lewintre, Carlos Camps, Lijie Grace Zhang

3D printing novel in vitro cancer cell culture model systems for lung cancer stem cell study

Materials Science and Engineering C · DOI: 10.1016/j.msec.2021.111914

Hoda Elkhenany, Pablo Bonilla, Esther Giraldo, Ana Alastrue Agudo, Michael J. Edel, María Jesus Vicent, Fernando Gisbert Roca, Cristina Martínez Ramos, Laura Rodríguez Doblado, Manuel Monleón Pradas, Victoria Moreno Manzano

A Hyaluronic Acid Demilune Scaffold and Polypyrrole-Coated Fibers Carrying Embedded Human Neural Precursor Cells and Curcumin for Surface Capping of Spinal Cord Injuries

Biomedicines · DOI: 10.3390/biomedicines9121928

Daniel Esteve, María Micaela Molina-Navarro, Esther Giraldo, Noelia Martínez-Varea, Mari-Carmen Blanco-Gandia, Marta Rodríguez-Arias, José Manuel García-Verdugo, José Viña, Ana Lloret

Adult Neural Stem Cell Migration Is Impaired in a Mouse Model of Alzheimer’s Disease

Molecular Neurobiology · DOI: 10.1007/s12035-021-02620-6

E. Giraldo, V.J. Nebot, S. Đorđević, R. Requejo‑Aguilar, A. Alastrue‑Agudo, O. Zagorodko, A. Armiñan, B. Martinez‑Rojas, M.J. Vicent, V. Moreno‑Manzano

A rationally designed self-immolative linker enhances the synergism between a polymer-rock inhibitor conjugate and neural progenitor cells in the treatment of spinal cord injury

Biomaterials · DOI: 10.1016/j.biomaterials.2021.121052

Pablo Bonilla, Joaquim Hernandez, Esther Giraldo, Miguel A. González‑Pérez, Ana Alastrue‑Agudo, Hoda Elkhenany, María J. Vicent, Xavier Navarro, Michael Edel, Victoria Moreno‑Manzano

Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment

International Journal of Molecular Sciences (IJMS) · DOI: 10.3390/ijms22115966

Paloma Monllor, Esther Giraldo, Mari-Carmen Badia, Jose Garcia de la Asuncion, Maria-Dolores Alonso, Ana Lloret, Jose Vina

Serum Levels of Clusterin, PKR, and RAGE Correlate with Amyloid Burden in Alzheimer’s Disease

Journal of Alzheimer’s Disease · DOI: 10.3233/JAD-201443

Esther Giraldo, David Palmero-Canton, Beatriz Martinez-Rojas, Maria del Mar Sanchez-Martin, Victoria Moreno-Manzano

Optogenetic Modulation of Neural Progenitor Cells Improves Neuroregenerative Potential

International Journal of Molecular Sciences (IJMS) · DOI: 10.1080/10715762.2020.1798002

Ana Lloret, Paloma Monllor, Tanja Fuchsberger, Esther Giraldo, Marzia Perluigi, Jose Vina

Increased basal antioxidant levels in RCAN1 – deficient mice lowers oxidative injury after acute paraquat insult

Free Radical Research · DOI: 10.3390/ijms22010365

Andrea Moreno‑Manuel, Silvia Calabuig‑Fariñas, Antonia Obrador‑Hevia, Ana Blasco, Amaya Fernández‑Díaz, Rafael Sirera, Carlos Camps, Eloisa Jantus‑Lewintre

dPCR application in liquid biopsies: divide and conquer

Expert Review of Molecular Diagnostics · DOI: 10.1080/14737159.2021.1860759

Atocha Romero, Eloisa Jantus-Lewintre, Beatriz García-Peláez, Ana Royuela, Amelia Insa, Patricia Cruz, Ana Collazo, Javier Pérez Altozano, Oscar Juan Vidal, Pilar Diz, Manuel Cobo, Berta Hernández, Sergio Vázquez Estevez, Gretel Benítez, Maria Guirado, Margarita Majem, Reyes Bernabé, Ana Laura Ortega, Ana Blasco, Joaquim Bosch-Barrera, Jose M. Jurado, Jorge García González, Santiago Viteri, Carlos Garcia Giron, Bartomeu Massutí, Ana Lopez Martín, Alejandro Rodriguez-Festa, Silvia Calabuig-Fariñas, Miguel Ángel Molina-Vila, Mariano Provencio

Comprehensive cross‐platform comparison of methods for non‐invasive EGFR mutation testing: Results of the RING observational trial

Molecular Oncology · DOI: 10.1002/1878-0261.12832

F. Zhang, N. Dong, M. Ferrero Gimeno, S. Calabuig‑Fariñas, S. Gallach, A. Blasco Cordellat, F.D.A. Aparisi Aparisi, M. Meri Abad, C. García González, G. D’Auria, R. Sirera Perez, E. Jantus Lewintre, C.J.C. Camps Herrero

1035P Effect of gut microbiota on immunotherapy of advanced NSCLC

Annals of Oncology · DOI: 10.1016/j.annonc.2020.08.1155

A. Moreno‑Manuel, S. Gallach Garcia, S. Calabuig‑Fariñas, A. Blasco Cordellat, M. Ferrero Gimeno, V. Ruiz Cordero, S. Torres Martinez, E. Duréndez, M. Mosqueda, E. Escorihuela, A. Fernandez Diaz, F.D.A. Aparisi Aparisi, E. Jantus Lewintre, C. Camps

1196P Identification of targetable alterations using NGS-based liquid biopsy in NSCLC patients

Annals of Oncology · DOI: 10.1016/j.annonc.2020.08.090

E. Duréndez Sáez, S. Calabuig‑Fariñas, C. Suarez, M. Ferrero Gimeno, M. Mosqueda, A. Moreno, S. Torres Martinez, A. Hererros‑Pomares, S. Gallach Garcia, M. Nunez Abad, A. Blasco Cordellat, F.D.A. Aparisi Aparisi, E. Serna, J.M. Paramio, E. Jantus Lewintre, C. Camps

1212P Exosomes cargo analysis as an approach to identify new biomarkers in NSCLC

Annals of Oncology · DOI: 10.1016/j.annonc.2020.08.106

N. Dong, A. Panizza, A. Moreno, S. Gallach, F. Zhang, M. Meri Abad, F.D.A. Aparisi Aparisi, A. Blasco Cordellat, I. Shaheen, M. Ferrero Gimeno, S. Calabuig‑Fariñas, E. Jantus Lewintre, C.J.C. Camps Herrero

1063P Profiling of peripheral T cell receptor beta chain repertoire in non-small cell lung cancer (NSCLC) patients treated with anti-PD1

Annals of Oncology · DOI: 10.1016/j.annonc.2020.08.1183

S. Gallach Garcia, J. Garde Noguera, S. Torres Martinez, F.D.A. Aparisi Aparisi, J. Vidal Martínez, E. Escorihuela, R. Gisbert Criado, A. Moreno, M. Ferrero Gimeno, M. Meri Abad, I. Shaheen, S. Calabuig‑Fariñas, A. Blasco Cordellat, B. Honrubia Peris, J. García Sánchez, E. Jantus Lewintre, C. Camps

1039P Analysis of predictive and prognostic soluble biomarkers in advanced non-small cell lung cancer (NSCLC) patients treated with anti-PD1/PDL1

Annals of Oncology · DOI: 10.1016/j.annonc.2020.08.1159

Andrea Moreno‑Manuel, Eloisa Jantus‑Lewintre, Ines Simões, Fernando Aranda, Silvia Calabuig‑Fariñas, Esther Carreras, Sheila Zúñiga, Yvonne Saenger, Rafael Rosell, Carlos Camps, Francisco Lozano, Rafael Sirera

CD5 and CD6 as immunoregulatory biomarkers in non-small cell lung cancer

Translational Lung Cancer Research · DOI: 10.21037/tlcr-19-445

Atocha Romero, Miguel Angel Molina-Vila, Eloisa Jantus-Lewintre, Amelia Insa, Patricia Cruz, Ana Collazo, Javier Perez Altozano, Oscar Juan-Vidal, Pilar Diz, Manuel Cobo, Berta Hernandez, Sergio Vazquez-Estevez, Gretel Benitez, Maria Guirado, Alejandro Rodriguez-Festa, Silvia Calabuig-Fariñas, Rafael Rosell, Carlos Camps, Ana Royuela, Mariano Provencio-Pulla

Comprehensive cross-platform comparison of methodologies for noninvasive EGFR mutation testing: Results of the RING observational trial.

Journal of Clinical Oncology · DOI: 10.1200/JCO.2020.38.15_suppl.e21518

Christian Rolfo, Andrés F. Cardona, Massimo Cristofanilli, Luis Paz‑Ares, Juan Jose Diaz Mochon, Ignacio Duran, Luis E. Raez, Alessandro Russo, Jose A. Lorente, Umberto Malapelle, Ignacio Gil‑Bazo, Eloisa Jantus‑Lewintre, Patrick Pauwels, Tony Mok, María José Serrano

Challenges and opportunities of cfDNA analysis implementation in clinical practice: Perspective of the International Society of Liquid Biopsy (ISLB)

Critical Reviews in Oncology/Hematology · DOI: 10.1016/j.critrevonc.2020.102978

Susana Torres, Álvaro González, Alberto Jacobo Cunquero Tomas, Silvia Calabuig Fariñas, Macarena Ferrero, Danielle Mirda, Rafael Sirera, Eloisa Jantus‑Lewintre, Carlos Camps

A profile on cobas® EGFR Mutation Test v2 as companion diagnostic for first-line treatment of patients with non-small cell lung cancer

Expert Review of Molecular Diagnostics · DOI: 10.1080/14737159.2020.1724094