

Projects
- 2024
- 2023
Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines (ERAMET). 101137141. European Commission – Horizon 2020 RIA. 2024–2027. Virginia Merino.
Aproximación farmacocinética, biofarmacéutica y tecnológica para la optimización de los tratamientos de enfermedades oculares inflamatorias y degenerativas. PID2022-142350OB-C22. Agencia Estatal de Investigación (AEI). 2023–2027. Virginia Merino.
Evaluación de la estructura interna de formulaciones tópicas semisólidas. CIAICO/2022/170. Generalitat Valenciana – CIAICO. 2023–2025. Virginia Merino Sanjuán.

Publications
- 2026
- 2025
- 2024
- 2023
- 2022
- 2021
- 2020
Gledys Reynaldo‑Fernandez, Leyanis Rodriguez‑Vera, Daniel Amaro, Joaquin Solozábal, Jorge Duconge, Victor Mangas‑Sanjuan, Iñaki F. Troconiz, Francine Johansson Azeredo, Valvanera Vozmediano
Forecasting the Biological Effect of PEGylated-rHuEPO Candidates in Chronic Kidney Disease Patients using a Middle-out Translation Approach
Pharmaceutical Research · DOI: 10.1007/s11095-025-04013-z
Karine Rodriguez‑Fernandez, José David Gómez‑Mantilla, Suneet Shukla, Victor Mangas‑Sanjuán, Sheila Annie Peters
Solubility-Limited Absorption Identified by a Simplified PBPK Model for the Prediction of Positive Food Effect for BCS II/IV Drugs
Clinical Pharmacokinetics · DOI: nan
Zhengguo Xu, Marina Cuquerella-Gilabert, Javier Zarzoso-Foj, Matilde Merino-Sanjuan, Victor Mangas-Sanjuan, Alfredo García-Arieta
Comparison of dissolution profiles: 90% confidence intervals of different f2 estimators using bootstrap methodology versus the Euclidean Distance of the Non-standardized Expected (EDNE) values
European Journal of Pharmaceutics and Biopharmaceutics · DOI: 10.1016/j.ejpb.2025.114839
Elena Godoy-Molina, Natalia L. Serrano, Aquilina Jiménez-González, Victor Mangas-Sanjuan, Francesc Palau
Elesclomol-copper therapy improves neurodevelopment in two children with Menkes disease
The Journal of clinical investigation · DOI: 10.1172/JCI193107
Javier Zarzoso-Foj, Marina Cuquerella-Gilabert, Matilde Merino-Sanjuan, Javier Reig-Lopez, Víctor Mangas-Sanjuán, Alfredo Garcia-Arieta
Physiologically-Based Biopharmaceutics Modeling for Ibuprofen: Identifying Key Formulation Parameter and Virtual Bioequivalence Assessment
Pharmaceutics · DOI: 10.3390/pharmaceutics17040408
Javier Reig-López, Xurxo García-Otero, Marina Cuquerella-Gilabert, Enrique Bandín-Vilar, Francisco J. Otero-Espinar, Anxo Fernández-Ferreiro, Víctor Mangas-Sanjuán, Virginia Merino, Pablo Aguiar, Matilde Merino-Sanjuán
A physiologically based pharmacokinetic model to describe [89Zr]Zr-DFO-Adalimumab specific activity after intravitreal administration to rats with endotoxin-induced uveitis
International Journal of Pharmaceutics · DOI: 10.1016/j.ijpharm.2025.125845
Karine Rodriguez‑Fernandez, José David Gómez‑Mantilla, Suneet Shukla, Peter Stopfer, Peter Sieger, Victor Mangas‑Sanjuán, Sheila Annie Peters
Evaluation of Solubility-Limited Absorption as a Surrogate to Predicting Positive Food Effect of BCS II/IV Drugs
Clinical Pharmacokinetics · DOI: 10.1007/s40262-025-01473-9
Iris M. Domenech-Monsell, Adrián M. Alambiaga-Caravaca, Lucía Bernat-Just, Virginia Merino, Vicent Rodilla, Cristina Balaguer-Fernández & Alicia López-Castellano
Innovative Famciclovir Eye Drop Formulations for Herpes Zoster Infections
Current Eye Research · DOI: 10.1080/02713683.2025.2472363
Karine Rodríguez-Fernández, Javier Zarzoso-Foj, Marina Saez-Bello, Almudena Mateu-Puchades, Antonio Martorell-Calatayud, Matilde Merino-Sanjuan, Elena Gras-Colomer, Monica Climente-Martí, Victor Mangas-Sanjuan
Model-Informed Precision Dosing for Personalized Ustekinumab Treatment in Plaque Psoriasis
Pharmaceutics · DOI: 10.3390/pharmaceutics16101295
Karine Rodriguez-Fernandez, Javier Zarzoso-Foj, Marina Saez-Bello, Almudena Mateu-Puchades, Antonio Martorell-Calatayud, Matilde Merino-Sanjuan, Elena Gras-Colomer, Monica Climente-Marti, Victor Mangas-Sanjuan
Personalized Secukinumab Treatment in Patients with Plaque Psoriasis Using Model-Informed Precision Dosing
Pharmaceutics · DOI: 10.3390/pharmaceutics16121576
Carlos Tamarit-Martínez, Lucía Bernat-Just, Carlos Bueno-López, Adrián M. Alambiaga-Caravaca, Virginia Merino, Alicia López-Castellano, Vicent Rodilla
An Antibacterial-Loaded PLA 3D-Printed Model for Temporary Prosthesis in Arthroplasty Infections: Evaluation of the Impact of Layer Thickness on the Mechanical Strength of a Construct and Drug Release
Pharmaceutics · DOI: 10.3390/pharmaceutics16091151
Andreu Mañez-Asensi, Mª Jesús Hernández, Víctor Mangas-Sanjuán, Ana Salvador, Matilde Merino-Sanjuán, Virginia Merino
Impact of Time on Parameters for Assessing the Microstructure Equivalence of Topical Products: Diclofenac 1% Emulsion as a Case Study
Pharmaceutics · DOI: 10.3390/pharmaceutics16060749
Javier Reig-López, Marina Cuquerella-Gilabert, Enrique Bandín-Vilar,Matilde Merino-Sanjuán, Víctor Mangas-Sanjuán, Alfredo García-Arieta
Bioequivalence risk assessment of oral formulations containing racemic ibuprofen through a chiral physiologically based pharmacokinetic model of ibuprofen enantiomers
European Journal of Pharmaceutics and Biopharmaceutics · DOI: 10.1016/j.ejpb.2024.114293
Gema J. Cabañero-Resta, Bárbara Sánchez-Dengra, Alejandro Ruiz-Picazo, Marival Bermejo, Virginia Merino, Isabel Gonzalez-Alvarez, Marta Gonzalez-Alvarez
Pharmaceutical Compounding in Veterinary Medicine: Suspension of Itraconazole
Pharmaceutics · DOI: 10.3390/pharmaceutics16050576
Gloria M. Alfosea-Cuadrado, Javier Zarzoso-Foj, Albert Adell, Alfonso A. Valverde-Navarro, Eva M. González-Soler, Víctor Mangas-Sanjuán, Arantxa Blasco-Serra
Population Pharmacokinetic–Pharmacodynamic Analysis of a Reserpine-Induced Myalgia Model in Rats
Pharmaceutics · DOI: 10.3390/pharmaceutics16081101
Marina Cuquerella-Gilabert, Javier Reig-López, Jenifer Serna, Almudena Rueda-Ferreiro, Matilde Merino-Sanjuan, Victor Mangas-Sanjuan, Sergio Sánchez-Herrero
Phys-DAT: A physiologically-based pharmacokinetic model for unraveling the dissolution, transit and absorption processes using PhysPK®
Computer Methods and Programs in Biomedicine · DOI: 10.1016/j.cmpb.2023.107929
Karine Rodríguez-Fernández, Gledys Reynaldo-Fernández, Stephanie Reyes-González, Camila de las Barreras, Leyanis Rodríguez-Vera, Cornelis Vlaar, Jean-Christophe M. Monbaliu, Torsten Stelzer, Jorge Duconge, Victor Mangas-Sanjuan
New insights into the role of VKORC1 polymorphisms for optimal warfarin dose selection in Caribbean Hispanic patients through an external validation of a population PK/PD model
Biomedicine & Pharmacotherapy · DOI: 10.1016/j.biopha.2023.115977
Enrique Bandín-Vilar, Francisco José Toja-Camba, María Vidal-Millares, María José Durán-Maseda, Marta Pou-Álvarez, Ana Castro-Balado, Olalla Maroñas, Almudena Gil-Rodríguez, Ángel Carracedo, Irene Zarra-Ferro, Dolors Soy, Anxo Fernández-Ferreiro, Víctor Mangas-Sanjuan, Cristina Mondelo-García
Towards precision medicine of long-acting aripiprazole through population pharmacokinetic modelling
Psychiatry Research · DOI: 10.1016/j.psychres.2024.115721
Iria Varela-Rey, Enrique Bandín-Vilar, Francisco José Toja-Camba, Antonio Cañizo-Outeiriño, Francisco Cajade-Pascual, Marcos Ortega-Hortas, Víctor Mangas-Sanjuan, Miguel González-Barcia, Irene Zarra-Ferro, Cristina Mondelo-García, Anxo Fernández-Ferreiro
Artificial Intelligence and Machine Learning Applications to Pharmacokinetic Modeling and Dose Prediction of Antibiotics: A Scoping Review
Antibiotics · DOI: 10.3390/antibiotics13121203
Isabel Gonzalez-Alvarez, Alejandro Ruiz-Picazo, Ruben Selles-Talavera, Andres Figueroa-Campos,Virginia Merino, Marival Bermejo, Marta Gonzalez-Alvarez
In Vivo Predictive Dissolution and Biopharmaceutic-Based In Silico Model to Explain Bioequivalence Results of Valsartan, a Biopharmaceutics Classification System Class IV Drug
Pharmaceutics · DOI: 10.3390/pharmaceutics16030390
Javier Reig-Lopez, Weifeng Tang, Carlos Fernandez-Teruel, Matilde Merino-Sanjuan, Victor Mangas-Sanjuan, David W. Boulton, Pradeep Sharma
Application of population physiologically based pharmacokinetic modelling to optimize target expression and clearance mechanisms of therapeutic monoclonal antibodies
British Journal of Clinical Pharmacology · DOI: 10.1111/bcp.15745
Maria Garcia-Cremades, Zinnia Patricia Parra-Guillen, Victor Mangas-Sanjuan, Hugo Geerts
Editorial: Innovative pharmacometric approaches to inform drug development and clinical use
Frontiers in Pharmacology · DOI: 10.3389/fphar.2023.1274139
Pablo Rodríguez-Belenguer, Eric March-Vila, Manuel Pastor, Victor Mangas-Sanjuan, Emilio Soria-Olivas
Usage of model combination in computational toxicology
Toxicology Letters · DOI: 10.1016/j.toxlet.2023.10.013
Pablo Rodriguez, Victor Mangas-Sanjuan, Emilio Soria Olivas, Manuel Pastor
Integrating Mechanistic and Toxicokinetic Information in Predictive Models of Cholestasis
Journal of Chemical Information and Modeling · DOI: 10.1021/acs.jcim.3c00945
P. Rodríguez Belenguer, Victor Mangas-Sanjuan, Emilio Soria Olivas, Manuel Pastor
P06-15: Evaluating the impact of molecule properties and structural pharmacokinetic models for predicting cholestasis
Toxicology Letters · DOI: 10.1016/S0378-4274(23)00519-2
Aymara Sancho-Araiz, Zinnia P. Parra-Guillen, Jean Bragard,Sergio Ardanza, Victor Mangas-Sanjuan, Iñaki F. Troco ́ niz
Mechanistic characterization of oscillatory patterns in unperturbed tumor growth dynamics: The interplay between cancer cells and components of tumor microenvironment
PLOS Computational Biology · DOI: 10.1371/journal.pcbi.1011507
Víctor Mangas-Sanjuán, Marta Simón, Esperanza González-Rojano, Dolores Ochoa, Francisco Abad-Santos, Manuel Román, Mercedes Ramos, Carlos Govantes, Alfredo García-Arieta
Alternative Pharmacokinetic Metrics in Single-Dose Studies to Ensure Bioequivalence of Prolonged-Release Products at Steady State—A Case Study
Pharmaceutics · DOI: 10.3390/pharmaceutics15020409
Jorge Duconge, Victor Mangas-Sanjuan, Gledys Reynaldo Fernández
Conceptos y aplicaciones de los parámetros farmacocinéticos: Una guía para el salón de clases
Journal of Pharmacy & Pharmacognosy Research · DOI: 10.56499/jppres22.1472_11.1.160
Alfredo García-Arieta, John Gordon, Luther Gwaza, Virginia Merino, Víctor Mangas-Sanjuan
Regulatory Requirements for the Development of Second-Entry Semisolid Topical Products in the European Union
Pharmaceutics · DOI: 10.3390/pharmaceutics15020601
Angélica Villanueva-Martínez, Virginia Merino, Adriana Ganem-Rondero
Transdermal formulations and strategies for the treatment of osteoporosis
Journal of Drug Delivery Science and Technology · DOI: 10.1016/j.jddst.2022.103111
Javier Reig-Lopez, Matilde Merino-Sanjuan, Alfredo García-Arieta, Victor Mangas-Sanjuan
A physiologically based pharmacokinetic model for open acid and lactone forms of atorvastatin and metabolites to assess the drug-gene interaction with SLCO1B1 polymorphisms
Biomedicine & Pharmacotherapy · DOI: 10.1016/j.biopha.2022.113914
Teresa García-Martínez, María Dolores Bellés-Medall, Maria García-Cremades, Raúl Ferrando-Piqueres, Victor Mangas-Sanjuán, Matilde Merino-Sanjuan
Population Pharmacokinetic/Pharmacodynamic Modelling of Daptomycin for Schedule Optimization in Patients with Renal Impairment
Pharmaceutics · DOI: 10.3390/pharmaceutics14102226
Karine Rodríguez-Fernandez, Elena Gras-Colomer, Monica Climente-Martí, Victor Mangas-Sanjuan, Matilde Merino-Sanjuan
Pharmacometric characterization of entero-hepatic circulation processes of orally administered formulations of amiodarone under complex binding kinetics
European Journal of Pharmaceutical Sciences · DOI: 10.1016/j.ejps.2022.106198
Karine Rodríguez-Fernández, Víctor Mangas-Sanjuán, Matilde Merino-Sanjuán, Antonio Martorell-Calatayud, Almudena Mateu-Puchades, Mónica Climente-Martí, Elena Gras-Colomer
Impact of Pharmacokinetic and Pharmacodynamic Properties of Monoclonal Antibodies in the Management of Psoriasis
Pharmaceutics · DOI: 10.3390/pharmaceutics14030654
Enrique Bandín‑Vilar, Laura García‑Quintanilla, Ana Castro‑Balado Irene Zarra‑Ferro1,2 ·Miguel González‑Barcia, Manuel Campos‑Toimil, Víctor Mangas‑Sanjuan, Cristina Mondelo‑García, Anxo Fernández‑Ferreiro
A Review of Population Pharmacokinetic Analyses of Linezolid
Clinical Pharmacokinetics · DOI: 10.1007/s40262-022-01125-2
Mark McAllister, Talia Flanagan, Susan Cole, Andreas Abend, Evangelos Kotzagiorgis, Jobst Limberg,Heather Mead, Victor Mangas-Sanjuan, Paul A. Dickinson, Andrea Moir, Xavier Pepin,Diansong Zhou, Christophe Tistaert, Aristides Dokoumetzidis, Om Anand, Maxime Le Merdy,David B. Turner, Brendan T. Griffin, Adam Darwich, Jennifer Dressman, Claire Mackie
Developing Clinically Relevant Dissolution Specifications (CRDSs) for Oral Drug Products: Virtual Webinar Series
Pharmaceutics · DOI: 10.3390/pharmaceutics14051010
Elena Gras-Colomer, Víctor Mangas-Sanjuán, María-Amparo Martínez-Gomez, Monica Climente-Martí, Matilde Merino-Sanjuan
Quantitative assessment of the exposure–efficacy relationship of glucocerebrosidase using Markovian elements in Gaucher patients treated with enzyme replacement therapy
British Journal of Clinical Pharmacology · DOI: 10.1111/bcp.15198
Aymara Sancho-Araiz, Sara Zalba, María J. Garrido, Pedro Berraondo, Brian Topp,Dinesh de Alwis 5, Zinnia P. Parra-Guillen, Víctor Mangas-Sanjuan, Iñaki F. Trocóniz
Semi-Mechanistic Model for the Antitumor Response of a Combination Cocktail of Immuno-Modulators in Non-Inflamed (Cold) Tumors
Cancers · DOI: 10.3390/cancers13205049
Francisco José Toja-Camba, Nerea Gesto-Antelo, Olalla Maroñas, Eduardo Echarri Arrieta,Irene Zarra-Ferro, Miguel González-Barcia, Enrique Bandín-Vilar, Victor Mangas Sanjuan, Fernando Facal, Manuel Arrojo Romero, Angel Carracedo, Cristina Mondelo-García, Anxo Fernández-Ferreiro
Review of Pharmacokinetics and Pharmacogenetics in Atypical Long-Acting Injectable Antipsychotics
Pharmaceutics · DOI: 10.3390/pharmaceutics13070935
Aymara Sancho-Araiz, Victor Mangas-Sanjuan, Iñaki F Trocóniz
The Role of Mathematical Models in Immuno-Oncology: Challenges and Future Perspectives
Pharmaceutics · DOI: 10.3390/pharmaceutics13071016
Begoña Porta-Oltra, Matilde Merino
Personalized pharmacotherapy in oncology: Application of pharmacokinetic-pharmacodynamic criteria
Farmacia Hospitalaria · DOI: 10.7399/fh.11777
I. Camara-Martinez, J.A. Blechar, A. Ruiz-Picazo, A. Garcia-Arieta, C. Calandria,V. Merino-Sanjuan, P. Langguth, M. Gonzalez-Alvarez, M. Bermejo, J. Al-Gousous, I. Gonzalez-Alvarez
Level A IVIVC for immediate release tablets confirms in vivo predictive dissolution testing for ibuprofen
International Journal of Pharmaceutics · DOI: 10.1016/j.ijpharm.2021.121415
Carlos Bueno-López, Carlos Tamarit-Martínez, Adrián M. Alambiaga-Caravaca, Cristina Balaguer-Fernández, Virginia Merino , Alicia López-Castellano, Vicent Rodilla
3D Printing of Temporary Prostheses for Controlled-Release of Drugs: Design, Physical Characterization and Preliminary Studies
Pharmaceutics · DOI: 10.3390/ph14121240
Adrián M. Alambiaga-Caravaca, Iris M. Domenech-Monsell, María Sebastián-Morelló, M. Aracely Calatayud-Pascual, Virginia Merino, Vicent Rodilla, Alicia López-Castellano
Development, characterization, and ex vivo evaluation of an insert for the ocular administration of progesterone
International Journal of Pharmaceutics · DOI: 10.1016/j.ijpharm.2021.120921
Mayank Singhal, César Serna, Virginia Merino, Yogeshvar N. Kalia
Current profile controlled transdermal delivery of pramipexole from an iontophoretic patch system in vitro and in vivo
European Journal of Pharmaceutics and Biopharmaceutics · DOI: 10.1016/j.ejpb.2021.06.010
Ana Moya-Gil, María Amparo Martínez-Gómez, Begoña Porta-Oltra, Matilde Merino-Sanjuán, Mónica Climente-Martí
Physico-Chemical Stability of Admixtures of Vinflunine Used in Clinical Practice
Journal of Pharmaceutical Sciences · DOI: 10.1016/j.xphs.2021.02.021
Javier Reig López, Alfredo García Arieta, Victor Mangas-Sanjuan, Matilde Merino
Current Evidence, Challenges, and Opportunities of Physiologically Based Pharmacokinetic Models of Atorvastatin for Decision Making
Pharmaceutics · DOI: 10.3390/pharmaceutics13050709
Zhengguo Xu, Matilde Merino, Victor Mangas-Sanjuan, Alfredo García Arieta
Estimators and Confidence Intervals of f 2 Using Bootstrap Methodology for the Comparison of Dissolution Profiles
Computer Methods and Programs in Biomedicine · DOI: 10.1016/j.cmpb.2021.106449
Lucía López-Sánchez, Pablo Miralles, Amparo Salvador, Matilde Merino-Sanjuán, Virginia Merino
In vitro skin penetration of bronidox, bronopol and formaldehyde from cosmetics
Regulatory Toxicology and Pharmacology · DOI: 10.1016/j.yrtph.2021.104888
Zhengguo Xu, Víctor Mangas-Sanjuán, Matilde Merino-Sanjuán,Virginia Merino, Alfredo García-Arieta
Influence of Inter- and Intra-Batch Variability on the Sample Size Required for Demonstration of Equivalent Microstructure of Semisolid Dosage Forms
Pharmaceutics · DOI: 10.3390/pharmaceutics12121159
Valeria Gigante, Giovanni M. Pauletti, Sabine Kopp, Minghze Xu, IsabelGonzalez-Alvarez, Virginia Merino, Michelle P. McIntosh, Anita Wessels, Beom-Jin Lee, Kênnia Rocha Rezende, Gerhard K.E. Scriba, Gaurav P. S. Jadaun, Marival Bermejo
Global testing of a consensus solubility assessment to enhance robustness of the WHO biopharmaceutical classification system
ADMET & DMPK · DOI: 10.5599/admet.850
Adrian H. Teruel, Isabel Gonzalez-Alvarez, Marival Bermejo, Virginia Merino, Maria Dolores Marcos, Felix Sancenon, Marta Gonzalez-Alvarez, Ramon Martinez-Mañez
New Insights of Oral Colonic Drug Delivery Systems for Inflammatory Bowel Disease Therapy
International Journal of Molecular Sciences (IJMS) · DOI: 10.3390/ijms21186502
Andrés Figueroa-Campos, Bárbara Sánchez-Dengra, Virginia Merino, Arik Dahan, Isabel González-Álvarez, Alfredo García-Arieta , Marta González-Álvarez, Marival Bermejo
Candesartan Cilexetil In Vitro–In Vivo Correlation: Predictive Dissolution as a Development Tool
Pharmaceutics · DOI: 10.3390/pharmaceutics12070633
Jordi Ocaña, Toni Monleón-Getino, Virginia Merino, Daniel Peris, Lluís Soler
Statistical Methods for Quality Equivalence of Topical Products. 0.5 mg/g Betamethasone Ointment as a Case-Study
Pharmaceutics · DOI: 10.3390/pharmaceutics12040318
Javier Reig-López, María del Mar Maldonado, Matilde Merino-Sanjuan, Ailed M. Cruz-Collazo, Jean F. Ruiz-Calderón, Victor Mangas-Sanjuán, Suranganie Dharmawardhane, Jorge Duconge
Physiologically-Based Pharmacokinetic/Pharmacodynamic Model of MBQ-167 to Predict Tumor Growth Inhibition in Mice
Pharmaceutics · DOI: 10.3390/pharmaceutics12100975
Marina Sáez-Belló, Víctor Mangas-Sanjuán, Mª. Amparo Martínez-Gómez, Mª. Angeles López-Montenegro Soria, Mónica Climente-Martí, Matilde Merino-Sanjuán
Evaluation of ABC gene polymorphisms on the pharmacokinetics and pharmacodynamics of capecitabine in colorectal patients: Implications for dosing recommendations
British Journal of Clinical Pharmacology · DOI: 10.1111/bcp.14441
Elena Gras Colomer, Victor Mangas-Sanjuan, Monica Climente, Matilde Merino
Population pharmacokinetic of enzymatic activity of glucocerebrosidase in Gaucher disease patients treated with enzyme replacement therapy
Molecular Genetics and Metabolism · DOI: 10.1016/j.ymgme.2019.11.160
Javier Reig López, Matilde Merino, Victor Mangas-Sanjuan, Manuel Prado-Velasco
A Multilevel Object-Oriented Modelling Methodology for Physiologically-Based Pharmacokinetics (PBPK): Evaluation with a Semi-Mechanistic Pharmacokinetic Model
Computer Methods and Programs in Biomedicine · DOI: 10.1016/j.cmpb.2020.105322
Darlene Santiago, Victor Mangas-Sanjuan, Kyle Melin, Jorge Duconge, Wenchen Zhao, Raman Venkataramanan
Pharmacokinetic Characterization and External Evaluation of a Quantitative Framework of Sublingual Buprenorphine in Patients with an Opioid Disorder in Puerto Rico
Pharmaceutics · DOI: 10.3390/pharmaceutics12121226
Niurys de Castro-Suárez, Mirjam N. Trame, Mayra Ramos-Suzarte, José M. Dávalos, Raymed A. Bacallao-Mendez, Anaelys R. Maceo-Sinabele, Víctor Mangas-Sanjuán, Gledys Reynaldo-Fernández, Leyanis Rodríguez-Vera
Semi-Mechanistic Pharmacokinetic Model to Guide the Dose Selection of Nimotuzumab in Patients with Autosomal Dominant Polycystic Kidney Disease
Pharmaceutics · DOI: 10.3390/pharmaceutics12121147
Sotirios Michaleas , Elisabeth Penninga , Doris Hovgaard , Anne‐Marie Dalseg , Aldana Rosso , Sinan B. Sarac , Jorge Camarero Jimenez , Lucia López‐Anglada Fernández , Carolina Prieto Fernández , Victor Mangas‐SanJuan
The European Medicines Agency review of daratumumab (Darzalex) for the treatment of adult patients newly diagnosed with multiple myeloma
The Oncologist · DOI: 10.1002/onco.13554
Stephanie Reyes-González , Camila de las Barreras , Gledys Reynaldo , Leyanis Rodríguez-Vera , Cornelis Vlaar , Vilmali Lopez Mejias , Jean-Christophe M. Monbaliu , Torsten Stelzer , Victor Mangas and Jorge Duconge
Genotype-driven pharmacokinetic simulations of warfarin levels in Puerto Ricans
Drug Metabolism and Personalized Therapy · DOI: 10.1515/dmdi-2020-0135
Lucas Noce, Luther Gwaza, Victor Mangas-Sanjuan, Alfredo García Arieta
Comparison of free software platforms for the calculation of the 90% confidence interval of f2 similarity factor by bootstrap analysis
European Journal of Pharmaceutical Sciences · DOI: 10.1016/j.ejps.2020.105259

Patents
- 2018
- 2016
Sistema de Liberación Controlada y Método de Preparación del Mismo. P201830512. Universitat Politècnica de València (UPV); Universitat de València (UV); Universidad Miguel Hernández (UMH).
H Teruel, Adrián; Martínez-Máñez, Ramón; Sancenón Galarza, Félix; VIRGINIA MERINO SANJUÁN.
Formulación para liberación modificada de sustancias activas o fármacos, uso y procedimiento de obtención. P201631463. Universidad Miguel Hernández (UMH); Universitat de València (UV); Consejo Superior de Investigaciones Científicas (CSIC); Universitat Politècnica de València (UPV).
Martínez-Martínez MT; González-Álvarez M; Bermejo-Sanz MV; Rodríguez-Berna G; Corma-Canós A; Merino- Sanjuán V.

